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三共研究所年報. 50

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操作方法

目次・巻号

  • 三共研究所年報
    • 1960~1969 (7)
    • 1970~1979 (10)
    • 1980~1989 (10)
    • 1990~1999 (10)
      • 1990 (1)
      • 1991 (1)
      • 1992 (1)
      • 1993 (1)
      • 1994 (1)
      • 1995 (1)
      • 1996 (1)
      • 1997 (1)
      • 1998 (1)
        • 50 [110]
          • Minireviews New Aspects in Carbapenem Antibiotics / Isao KAWAMOTO ; Satoshi OHYA/p1~14
          • Minireviews Application of Underutilized Microbial Resources in Drug Discovery: A Review Focused on Discomycetes / Tsuyoshi HOSOYA/p15~40
          • Minireviews Application of Digital Microradiography in Experimental Adjuvant-induced Arthritis Rats / Kuniaki FUKUDA ; Yositake FURUTA ; Seiko MASUDA ; Shigeru USHIYAMA/p41~45
          • Minireviews Evaluation of Ophthalmic Toxicity and Ototoxicity Using Electrophysiological Methods / Tomofumi OKAMOTO/p47~59
          • Minireviews Research and Development of Throw-in-pack Herbicide for Paddy Field, Kusatory-Ace® Jumbo¹⁾~¹⁵⁾ / Toyokuni HONMA ; Kinji TANIZAWA ; Tsuyoshi HIRATA ; Hiroshi SABI ; Junji KADOTANI ; Masahiro TERAMURA ; Masayuki NAKAGAWA ; Masahiko FUJIMOTO ; Akihiko KUNITOMO/p61~70
          • Notes Immunohistochemical Comparison of Localization of Cytochrome P450 Isozymes in the Rat Liver Treated with Prototype Drug-metabolizing Enzyme Inducers / Isao IGARASHI ; Yoshihiko OHASHI ; Toshiyuki WATANABE ; Masaya TAKAOKA ; Takashi YAMOTO ; Sunao MANABE/p71~77
          • Notes Application of Telemetry System to Evaluate Daily Variation of Multiple Physiological Variables in Rats / Yasuhiro KINPARA ; Satoru SHARYO ; Tadashi FURUKAWA ; Sunao MANABE/p79~85
          • Abstracts of papers published in scientific journals //p87~168
          • Review Articles Troglitazone―A Novel Antidiabetic Drug for Treating Insulin Resistance / Hiroyoshi HORIKOSHI ; Takao YOSHIOKA/p87~87
          • Review Articles 1β-Methylcarbapenem Antibiotics / Isao KAWAMOTO/p87~87
          • Review Articles Future Aspects of Treatments of Rheumatoid Arthritis Using Agents from Biological Sources / Akio SHIRAISHI/p87~88
          • Review Articles Development of New Medicine in 21st Century; Antidiabetic Drugs / Hiroyoshi HORIKOSHI/p88~89
          • Review Articles A Consideration about Scale-up Process / Masahiko HOSOBUCHI/p89~89
          • Review Articles Research Development and Pharmacology of HMG-CoA Reductase Inhibitors / Yoshio TSUJITA/p89~90
          • Physical & Analytical Chemistry Simultaneous Determination of Alkali Metal Ions by Ion Chromatography Using a Graphitized Carbon Column / Toshimitsu OKAMOTO ; Kazuo TAKAYAMA ; Masaru IKEDA ; Hisomu NAGASHIMA/p90~91
          • Physical & Analytical Chemistry Solution Structure of CINC/Gro Investigated by Heteronuclear NMR / Hiroyuki HANZAWA ; Hideyuki HARUYAMA ; Kiyoshi KONISHI ; Kazuyoshi WATANABE ; Susumu TSURUFUJI/p91~92
          • Physical & Analytical Chemistry Studies on Elution Conditions for the Determination of Anions by Suppressed Ion-interaction Chromatography Using a Graphitized Carbon Column / Toshimitsu OKAMOTO ; Akinori ISOZAKI ; Hisomu NAGASHIMA/p92~93
          • Physical & Analytical Chemistry Metastable and Collision-induced Dissociations of Organosilicon Compounds / Susumu TAJIMA ; Shigeru MORI ; Takeshi KINOSHITA ; Hisao NAKATA/p93~93
          • Physical & Analytical Chemistry Structure Determination of Metabolites and Investigation of Metabolic Pathway Using Mass Spectrometry in Drug Metabolism / Haruo IWABUCHI/p94~94
          • Physical & Analytical Chemistry Structural Determination of Rat and Dog Urinary Metabolites of a New Antidepressant RS-8359 / Haruo IWABUCHI ; Wataru TAKASAKI ; Harumitsu KUWANO ; Takashi KOBAYASHI ; Yorihisa TANAKA/p94~95
          • Organic Chemistry Structure-activity Relationship of HIV-1 Protease Inhibitors Containing AHPBA. Part 3: Modification of P₂ Site / Eiji TAKASHIRO ; Takashi WATANABE ; Tamayo NITTA ; Atsushi KASUYA ; Shuichi MIYAMOTO ; Yuji OZAWA ; Ryuichi YAGI ; Takashi NISHIGAKI ; Takahiro SHIBAYAMA ; Akihiko NAKAGAWA ; Aikichi IWAMOTO ; Yuichiro YABE/p95~96
          • Organic Chemistry Synthesis and 5α-Reductase Inhibitory Activities of Benzofuran Derivatives with a Carbamoyl Group / Koki ISHIBASHI ; Katsuyoshi NAKAJIMA ; Yuki SUGIOKA ; Mitsuo SUGIYAMA ; Takakazu HAMADA ; Hiroyoshi HORIKOSHI ; Takahide NISHI/p96~96
          • Organic Chemistry A Practical and Stereocontrolled Synthesis of a Versatile 1β-Methylcarbapenem Intermediate / Kozo ODA ; Akira YOSHIDA/p97~97
          • Organic Chemistry [2-(ω-Phenylalkyl)phenoxy]alkylamines: Synthesis and Dual Dopamine₂ (D₂)and 5-Hydroxytryptamine₂(5-HT₂) Receptor Antagonistic Activities / Naoki TANAKA ; Riki GOTO ; Rie ITO ; Miho HAYAKAWA ; Taketoshi OGAWA ; Koichi FUJIMOTO/p97~98
          • Organic Chemistry Practical Synthesis of 1β-Methylcarbapenem Antibiotics: Sidechain Substitution Reaction of 2- Arylsulfinyl and 2-Arylsulfonyl Carbapenems / Kozo ODA ; Akira YOSHIDA/p98~98
          • Organic Chemistry A Novel Oral Carbapenem CS-834: Chemical Stability of Pivaloyloxymethyl Esters of Carbapenems and Cephalosporins in Phosphate Buffer Solution / Masao MIYAUCHI ; Osamu KANNO ; Isao KAWAMOTO/p98~99
          • Organic Chemistry Synthesis and Structure-activity Relationships of 1β-Methylcarbapenems with Quaternary Ammonium Side Chains / Katsuya ISHIKAWA ; Katsuhiko KOJIMA ; Masao MIYAUCHI ; Rokuro ENDO ; Hiroshi YASUDA ; Isao KAWAMOTO/p99~100
          • Organic Chemistry Biologically Active Oligodeoxyribonucleotides (5) 5'-End-substituted d(TGGGAG) Possesses Anti-human Immunodeficiency Virus Type 1 Activity by Forming a G-quadruplex Structure / Hitoshi HOTODA ; Makoto KOIZUMI ; Rika KOGA ; Masakatsu KANEKO ; Kenji MOMOTA ; Toshinori OHMINE ; Hidehiko FURUKAWA ; Toshinori AGATSUMA ; Takashi NISHIGAKI ; Junko SONE ; Shinya TSUTSUMI ; Toshiyuki KOSAKA ; Koji ABE ; Satoshi KIMURA ; Kaoru SHIMADA/p100~101
          • Organic Chemistry Absolute Configuraion and Total Synthesis of (+)- Epolactaene, a Neuritogenic Agent from Penicillium sp. BM 1689-P Active in Human Neuroblastoma Cells / Shinji MARUMOTO ; Hiroshi KOGEN ; Shunji NARUTO/p101~102
          • Organic Chemistry Syntheses of 2,6-Anhydro-3-deoxy-5-O-phosphono-3-tetradecanamido-4-O-[(R)-3-tetradecanoyloxy) tetradecanoyl]-D-glycero-D-ido-heptonic Acid, Its Dimeric Analogue, and Related Compounds / Masao SHIOZAKI ; Shin-ichi KURAKATA ; Tohru TATSUTA ; Hiroaki MAEDA ; Masahiro NISHIJIMA/p102~103
          • Organic Chemistry Revised Structure and Synthesis of Flavolipin / Masao SHIOZAKI ; Noriko DEGUCHI ; Takashi MOCHIZUKI ; Takanori WAKABAYASHI ; Tomio ISHIKAWA ; Hideyuki HARUYAMA ; Yohko KAWAI ; Masahiro NISHIJIMA/p103~103
          • Organic Chemistry Side Chain Substitution Reaction of 2-Arylsulfinyl and 2-Arylsulfonyl Intermediates for 1β-Methylcarbapenems / Kozo ODA ; Akira YOSHIDA/p103~104
          • Organic Chemistry Synthesis of 1-Deoxynojirimycin-trehalamine Fused Compound and Its Related Compounds / Masao SHIOZAKI ; Osamu UBUKATA ; Hideyuki HARUYAMA ; Reiko YOSHIIKE/p104~104
          • Organic Chemistry Revised Structure of Flavolipin and Synthesis of Its Isomers / Masao SHIOZAKI ; Noriko DEGUCHI ; Tomio ISHIKAWA ; Hideyuki HARUYAMA ; Yohko KAWAI ; Masahiro NISHIJIMA/p104~105
          • Organic Chemistry AgOTfa/SnCl₄: A Powerful New Promoter Combination in the Aryl C-glycosidation of a Diverse Range of Sugar Acetates and Aromatic Substrates / Takeshi KURIBAYASHI ; Nobuyuki OHKAWA ; Susumu SATOH/p105~105
          • Organic Chemistry The Sequential Double Aryl C-glycosidation: Introduction of a Second Sugar Unit onto Mono Aryl C-glycosides Using SnCl₄/AgOTfa / Takeshi KURIBAYASHI ; Nobuyuki OHKAWA ; Susumu SATOH/p105~106
          • Natural Product Chemistry Structural Elucidation of Scyphostatin, an Inhibitor of Membrane-bound Neutral Sphingomyelinase / Masahiro TANAKA ; Futoshi NARA ; Keiko SUZUKI-KONAGAI ; Tsuyoshi HOSOYA ; Takeshi OGITA/p106~106
          • Natural Product Chemistry Thiomarinols D, E, F and G, New Hybrid Antimicrobial Antibiotics Produced by a Marine Bacterium; Isolation, Structure, and Antimicrobial Activity / Hideyuki SHIOZAWA ; Atsuko SHIMADA ; Shuji TAKAHASHI/p107~107
          • Natural Product Chemistry A Novel Bone Resorption Inhibitor, A-75943 Isolated from Streptomyces sp. SANK 61296 / Tadaaki MORISHITA ; Aiya SATO ; Tomoko ANDO ; Kiyoshi OIZUMI ; Masaaki MIYAMOTO ; Ryuzo ENOKITA ; Takao OKAZAKI/p107~108
          • Natural Product Chemistry A-53930A and B, Novel N-type Ca²⁺ Channel Blockers / Marie HISAMOTO ; Yoshinori INAOKA ; Yoshiharu SAKAIDA ; Takeshi KAGAZAKI ; Ryuzo ENOKIDA ; Takao OKAZAKI ; Hideyuki HARUYAMA ; Takeshi KINOSHITA ; Keiichi MATSUDA/p108~109
          • Natural Product Chemistry Cytotoxic Scalarane Sesterterpenes from a Sponge, Hyrtios erecta / Naoko TSUCHIYA ; Aiya SATO ; Tadashi HATA ; Noriko SATO ; Kazuhiko SASAGAWA ; Tomowo KOBAYASHI/p109~109
          • Natural Product Chemistry Nahocols and Isonahocols, Endothelin Antagonists from the Brown Alga, Sargassum autumnale / Naoko TSUCHIYA ; Aiya SATO ; Hideyuki HARUYAMA ; Tohru WATANABE ; Yasuteru IIJIMA/p110~110
          • Natural Product Chemistry Retrodihydrochalcones and Homoisoflavones Isolated from Thai Medicinal Plant Dracaena loureiri and Their Estrogen Agonist Activity / Kazuo ICHIKAWA ; Masahiro KITAOKA ; Motohiko TAKI ; Sachiko TAKAISHI ; Yasuteru IIJIMA ; Malee BORIBOON ; Toshiyuki AKIYAMA/p111~111
          • Natural Product Chemistry Prenylflavonoids: A New Class of Non-steroidal Phytoestrogen (Part 1) :Isolation of 8-Isopentenylnaringenin and an Initial Study on its Structure-activity Relationship / Masahiro KITAOKA ; Hiroshi KADOKAWA ; Machiko SUGANO ; Kazuo ICHIKAWA ; Motohiko TAKI ; Sachiko TAKAISHI ; Yasuteru IIJIMA ; Shinya TSUTSUMI ; Malee BORIBOON ; Toshiyuki AKIYAMA/p111~112
          • Cell & Gene Direct Formation of Human Interleukin-11 by Cis-acting System of Plant Virus Protease in Escherichia coli / Tohru TAKAHASHI ; Michiko NAKANISHI ; Yoshio YAO ; Ichiro UEDA ; Nobufusa SERIZAWA/p112~113
          • Cell & Gene Induction of Oral Tolerance in Splenocyte-reconstituted SCID Mice / Hiroko YOSHIDA ; Satoshi HACHIMURA ; Kazuki HIRAHARA ; Tatsuhiro HISATSUNE ; Ken-ichi NISHIJIMA ; Akio SHIRAISHI ; Shuichi KAMINOGAWA/p113~114
          • Cell & Gene Molecular Approaches for Production of Pravastatin, a HMG-CoA Reductase Inhibitor: Transcriptional Regulation of the Cytochrome P450sca Gene from Streptomyces carbophilus by ML-236B Sodium Salt and Phenobarbital / Ichiro WATANABE ; Nobufusa SERIZAWA/p114~114
          • Cell & Gene Characterization of One Monoclonal Antibody against Feline Immunodeficiency Virus p24 and Its Application to Antigen Capture ELISA / Hiroto KASHIWASE ; Masako ISHIMURA ; Yasuko ISHIKAWA ; Takashi NISHIGAKI/p115~115
          • Cell & Gene Various Roles of Membrane-bound Metalloproteases / Kazuhiko TANZAWA/p115~116
          • Biochemistry Racemization of β-Amyloid Protein: Role of Racemized β-Amyloids in Alzheimer's Disease / Isao KANEKO/p116~117
          • Biochemistry Inhibitors of Interleukin-1β-converting Enzyme-family Proteases (Caspases)Prevent Apoptosis without Affecting Decreased Cellular Ability to Reduce 3-(4,5- Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide in Cerebellar Granule Neurons / Jun HARADA ; Masahiko SUGIMOTO/p117~118
          • Biochemistry Characterization of the Lipid-carrier Involved in the Synthesis of Enterobacterial Common Antigen (ECA) and Identification of a Novel Phosphoglyceride in a Mutant of Salmonella typhimurium Defective in ECA Synthesis / PAUL D. Rick ; GAIL L. Hubbard ; Masahiro KITAOKA ; Hidemi NAGAKI ; Takeshi KINOSHITA ; Susan DOWD ; Virgil SIMPLACEANU ; Chien HO/p118~119
          • Biochemistry A Low Catalase Activity in Dog Erythrocytes Is Due to a Very Low Content of Catalase Protein Despite Having a Normal Specific Activity / Kouichi NAKAMURA ; Misa WATANABE ; Satsuki SAWAI-TANIMOTO ; Toshihiko IKEDA/p119~119
          • Antimicrobials In Vitro and In Vivo Antibacterial Activities of CS-834, a Novel Oral Carbapenem / Takashi FUKUOKA ; Satoshi OHYA ; Yukio UTSUI ; Haruki DOMON ; Takashi TAKENOUCHI ; Tetsufumi KOGA ; Nobuhisa MASUDA ; Harumi KAWADA ; Masayo KAKUTA ; Mikie KUBOTA ; Chie ISHII ; Chika ISHII ; Eiko SAKAGAWA ; Tamako HARASAKI ; Akiko HIRASAWA ; Tomomi ABE ; Hiroshi YASUDA ; Masayuki IWATA ; Shogo KUWAHARA/p120~121
          • Antimicrobials Efficacy of CS-834 against Experimental Pneumonia Caused by Penicillin-susceptible and -resistant Streptococcus pneumoniae in Mice / Takashi FUKUOKA ; Harumi KAWADA ; Akiko KITAYAMA ; Tetsufumi KOGA ; Mikie KUBOTA ; Tamako HARASAKI ; Yasuki KAMAI ; Satoshi OHYA ; Hiroshi YASUDA ; Masayuki IWATA ; Shogo KUWAHARA/p121~122
          • Antimicrobials Anti-human Immunodeficiency Virus Type 1 Activity of R-95288, a Phosphodiester Hexadeoxyribonucleotide Modified by Dibenzyloxybenzyl and Hydroxyethyl Residues at the 5'- and 3'-Ends / Toshinori AGATSUMA ; Hidehiko FURUKAWA ; Hitoshi HOTODA ; Makoto KOIZUMI ; Rika KOGA ; Masakatsu KANEKO/p122~122
          • Antimicrobials Antiviral and Biological Properties of Dimethoxytrityl-linked Guanine-rich Oligodeoxynucleotides that Inhibit Replication by Primary Clinical Human Immunodeficiency Virus Type 1 Isolates / Kenji MOMOTA ; Hidehiko FURUKAWA ; Satoshi KIMURA ; Hitoshi HOTODA ; Shinichi OKA ; Kaoru SHIMADA/p123~124
          • Antimicrobials Inhibitory Activity to Protein Prenylation and Antifungal Activity of Zaragozic Acid D3, a Potent Inhibitor of Squalene Synthase Produced by the Fungus, Mollisia sp. SANK 10294 / Tatsuo TANIMOTO ; Satoshi OHYA ; Yoshio TSUJITA/p124~124
          • Antimicrobials Interactions of Plaunotol with Bacterial Membranes / Tetsufumi KOGA ; Hidetoshi WATANABE ; Harumi KAWADA ; Keigo TAKAHASHI ; Yukio UTSUI ; Haruki DOMON ; Chika ISHII ; Teruo NARITA ; Hiroshi YASUDA/p125~125
          • Antimicrobials In-vitro and In-vivo Antibacterial Activities of CS-834, a New Oral Carbapenem / Eiko SAKAGAWA ; Masako OTSUKI ; Takanori OU ; Takeshi NISHINO/p126~126
          • Antimicrobials Outer Membrane Permeability and Effect of Basic Amino Acids on Antipseudomonal Activity of Carbapenems / Satoshi OHYA ; Nobuhisa MASUDA ; Eiko SAKAGAWA/p126~127
          • Antimicrobials Biologically Active Oligodeoxyribonucleotides (10) Anti-HIV-1 Activity and Stability of Modified Hexanucleotides Containing Glycerol-skeleton / Hitoshi HOTODA ; Makoto KOIZUMI ; Toshinori OHMINE ; Hidehiko FURUKAWA ; Takashi NISHIGAKI ; Koji ABE ; Toshiyuki KOSAKA ; Shinya TSUTSUMI ; Junko SONE ; Masakatsu KANEKO ; Satoshi KIMURA ; Kaoru SHIMADA/p127~128
          • Microbiology & Fermentation Process Development for High-level Secretory Production of Carboxypeptidase Y by Saccharomyces cerevisiae / Yoichiro SHIBA ; Fumio FUKUI ; Kimihisa ICHIKAWA ; Nobufusa SERIZAWA ; Hiroji YOSHIKAWA/p128~129
          • Microbiology & Fermentation Hyaloscyphaceae in Japan(1)Non-glassy-haired Members of the Tribe Hyaloscypheae / Tsuyoshi HOSOYA ; Yoshio OTANI/p129~129
          • Microbiology & Fermentation Hyaloscyphaceae in Japan(2)Glassy-haired Members of the Tribe Hyaloscypheae / Tsuyoshi HOSOYA ; Yoshio OTANI/p129~130
          • Microbiology & Fermentation Lambertella advenula, a New Combination Proposed for Moellerodiscus advenulus, New to Japan / Tsuyoshi HOSOYA ; Yoshio OTANI/p130~130
          • Microbiology & Fermentation Zaragozic Acids Production from Discomycetes / Tsuyoshi HOSOYA ; Tatsuo TANIMOTO ; Kaori ONODERA ; Yuko KURIHARA ; Yasuyuki TAKAMATSU ; Yoshio TSUJITA/p130~131
          • Microbiology & Fermentation Collection, Detection and Isolation of Fungi: Leotialean Discomycetes / Tsuyoshi HOSOYA/p131~131
          • Microbiology & Fermentation Discovery Research for Novel Bioactive Metabolites from Discomycetes in Japan, in Particular, Hyaloscyphaceae / Tsuyoshi HOSOYA/p131~132
          • Toxicology An Attempt to Predict the Response of Human Glutathione S-Transferase (GST) to Chemical Inducers Using Transgenic Rats Harboring Human GST Gene / Sunao MANABE ; Yosuke ANDO ; Yoshihiko OHASHI ; IsaoIGARASHI ; Takashi YAMOTO ; Masaya TAKAOKA ; Hisao TANASE ; Naochika MATSUNUMA ; Takashige SUZUKI ; Kazumi ITOH/p132~133
          • Toxicology Comparison of the Induction Profile of Hepatic Drug-metabolizing Enzymes between Piperonyl Butoxide and Phenobarbital in Rats / Toshiyuki WATANABE ; Sunao MANABE ; Yoshihiko OHASHI ; Hideaki OKAMIYA ; Hiroshi ONODERA ; Kunitoshi MITSUMORI/p133~134
          • Toxicology Effect of Glucose Feeding on Regenerating Rat Liver Following Partial Hepatectomy / Kohji TANAKA ; Isao IGARASHI ; Yoshihiko OHASHI ; Kazuo YAMASHITA ; Munehiro TERANISHI ; Takashi YAMOTO ; Masaya TAKAOKA ; Sunao MANABE/p134~135
          • Toxicology Comparison of Age-related Bone Changes between Mini Rats and Wistar Rats / Munehiro TERANISHI ; Yoshiro TANI ; Sunao MANABE/p135~135
          • Toxicology Differences in Immune Responses to Antibiotics in Three Guinea-pig Strains / Tetsuo AIDA ; Nobuhiro ISHIKAWA ; Kenkichi SHINKAI/p135~136
          • Toxicology Sex Differences in Immune Responses to Cephalothin in Guinea Pigs / Tetsuo AIDA ; Nobuhiro ISHIKAWA ; Kenkichi SHINKAI/p136~136
          • Toxicology Toxicity Evaluation of HMG-CoA Reductase Inhibitors in Experimental Animals / Junichiro FUKUSHIGE ; Yoshiro TANI/p137~137
          • Toxicology Single Dose Oral Toxicity Studies on CS-518 in Mice, Rats and Dogs / Kunio KIMURA ; Mitsuya YASUDA ; Kazuo YAMASHITA ; Satoshi ISHIZUKI/p137~138
          • Toxicology Toxicity Study in Dogs Treated Orally with CS-518 for 90 Days / Seiji SUDOU ; Kazuo YAMASHITA ; Yoshihiko OHASHI ; Masaya TAKAOKA ; Masahiro MORI ; Tadahiko OKADA/p138~139
          • Toxicology Reproduction Study of CS-518 Administered during Fetal Organogenesis in Rabbits / Tsutomu KIMURA ; Koichi HIROSE ; Hisao TANASE/p139~140
          • Toxicology Antigenicity Studies on CS-518 in Guinea Pigs and Mice / Kenkichi SHINKAI ; Tsutomu KIMURA ; Nobuhiro ISHIKAWA ; Keiko MURAMATSU ; Yukiko KURITA/p140~141
          • Toxicology Genotoxicity Tests on CS-518 / Kouichi HIRANO ; Toshiyuki HAGIWARA ; Atsushi HYOGO ; Tomoko HASEGAWA ; Ayuko KAWAGUCHI/p141~141
          • Toxicology A 52-Week Repeated Oral Dose Toxicity Study of Azelnidipine in Rats / Shuzo OKAZAKI ; Susumu NISHIMURA ; Kazuhisa HATAKEYAMA ; Kazutoshi TAMURA ; Takashi YAMOTO/p142~142
          • Pathology Rapid Induction of Liver Cirrhosis in Mini Rats by Thioacetamide / Yoshiro TANI ; Shinji MURATA ; Sachiko KAJIWARA ; Hatsue MIZUNO ; Junichiro FUKUSHIGE ; Tsunemichi HOSOKAWA ; Koji UETSUKA ; Hiroyuki NAKAYAMA ; Kunio DOI/p142~143
          • Pharmacology Lipid Lowering Effects of Pravastatin in Common Marmosets / Atsuhiro MIYAZAKI ; Teiichiro KOGA/p143~144
          • Pharmacology Amelioration of Insulin Resistance by Troglitazone and its Mechanism of Action / Hiroyoshi HORIKOSHI/p144~144
          • Pharmacology Troglitazone(CS-045) Potentiates Glucose-induced Biphasic Insulin Secretion in the Absence of Potentiation of Ca²⁺ Signaling in Rat Pancreatic Islets / Koichi NIWA ; Hiroyoshi HORIKOSHI ; Tomio SUGANO/p145~145
          • Pharmacology Involvement of Platelet-derived 5-Hydroxytryptamine in Thromboxane A₂₋induced Aggregation in Cat Platelets / Taketoshi OGAWA ; Atsuhiro SUGIDACHI ; Fumitoshi ASAI ; Hiroyuki KOIKE/p145~146
          • Pharmacology Thiazolidinediones Are Novel Insulin-sensitizing Agents / Alan R. SALTIEL ; Hiroyoshi HORIKOSHI/p146~147
          • Pharmacology Effects of Troglitazone (CS-045) on Insulin Secretion in Isolated Rat Pancreatic Islets and HIT Cells: An Insulinotropic Mechanism Distinct from Benclamide / Kazuhiro MASUDA ; Yoshimasa OKAMOTO ; Yoshiyuki TSUURA ; Seika KATO ; Toshihiro MIURA ; Kinsuke TSUDA ; Hiroyoshi HORIKOSHI ; Hitoshi ISHIDA ; Yutaka SEINO/p147~148
          • Pharmacology Effects of R-84760, a Selective κ-Opioid Receptor Agonist, on Nociceptive Reflex in Isolated Neonatal Rat Spinal Cord / Kenji FUJIBAYASHI ; Kazufumi KUBOTA ; Koji SAITO/p148~148
          • Pharmacology Enhancing Effect of Dimethyl Sulfoxide on Nociceptive Transmission in Isolated Spinal Cord of Newborn Rat / Kazufumi KUBOTA ; Kenji FUJIBAYASHI ; Koji SAITO/p149~149
          • Pharmacology Effect of Matrix Metalloproteinase Inhibitor on Pseudomonal Proteinases / Kazuhiro KOSAKU ; Naoyuki MAEDA ; Tomihisa YOKOYAMA ; Tatsuya INOUE ; Yumiko YOSHIDA ; Tsunemichi HOSOKAWA ; Mitsuru SAWA/p149~150
          • Pharmacology Delayed Healing of Chronic Gastric Ulcer after Helicobacter pylori Infection in Mice / Mitsuko MAKINO ; Tetsufumi KOGA ; Keiichi ITO ; Harumi KAWADA ; Keiichi TABATA/p150~151
          • Pharmacology Selective Allosteric Enhancement of the Binding and Actions of Acetylcholine at Muscarinic Receptor Subtypes / Nigel J.M. BIRDSALL ; Tim FARRIES ; Parviz GHARAGOZLOO ; Donald KUONEN ; Sebastian LAZARENO ; Angela POPHAM ; Shinsaku KOBAYASHI ; Masahiko SUGIMOTO/p151~152
          • Pharmacology Co-injection of β-Amyloid with Ibotenic Acid Induces Synergistic Loss of Rat Hippocampal Neurons / Kiyoshi MORIMOTO ; Kenji YOSHIMI ; Toshiyuki TONOHIRO ; Noriko YAMADA ; Tomiichiro ODA ; Isao KANEKO/p152~153
          • Pharmacology Effect of Plaunotol on Trinitrobenzene Sulfonic Acid-and Acetic Acid-Induced Colonic Lesions in Rats / Mitsuko MAKINO ; Yuka INOMATA ; Keiichi ITO ; Keiichi TABATA/p153~153
          • Pharmacology Troglitazone, its Pharmacology and Mechanism of Action / Hiroyoshi HORIKOSHI ; Toshihiko FUJIWARA/p154~154
          • Pharmacology Prenylflavonoids: A New Class of Non-steroidal Phytoestrogen (Part 2) :Estrogenic Effects of 8- Isopentenylnaringenin on Bone Metabolism / Masaaki MIYAMOTO ; Yoichi MATSUSHITA ; Akiko KIYOKAWA ; Chie FUKUDA ; Yasuteru IIJIMA ; Machiko SUGANO ; Toshiyuki AKIYAMA/p154~155
          • Pharmacology Non Insulin Secretagogues: Effects of Troglitazone on the Amelioration of Insulin Resistance / Hiroyoshi HORIKOSHI/p155~155
          • Pharmacology Inhibition of Rat Platelet Aggregation by Mycalolide-B, a Novel Inhibitor of Actin Polymerization with a Different Mechanism of Action from Cytochalasin-D / Atsuhiro SUGIDACHI ; Taketoshi OGAWA ; Fumitoshi ASAI ; Shinya SAITO ; Hiroshi OZAKI ; Nobuhiro FUSETANI ; Hideaki KARAKI ; Hiroyuki KOIKE/p155~156
          • Pharmacokinetics Safety and Pharmacokinetics of CS-834, a New Oral Carbapenem Antibiotic, in Healthy Volunteers / Kazuo UMEMURA ; Yasuhiko IKEDA ; Kazunao KONDO ; Mitsuyoshi NAKASHIMA ; Hideo NAGANUMA ; Masafumi HISAOKA ; Hiroshi NISHINO ; Masazo TAJIMA/p156~157
          • Pharmacokinetics Metabolism of Pravastatin Sodium by 3α-Hydroxysteroid Dehydrogenase / Shigeki MURAMATSU ; Yuko KOMOKATA ; Yorihisa TANAKA ; Hidekuni TAKAHAGI/p158~158
          • Pharmacokinetics Effect of Panipenem on the Pharmacokinetics of Valproic Acid in Dogs / Naotoshi YAMAMURA ; Kaoru IMURA ; Hideo NAGANUMA/p158~159
          • Pharmacokinetics Hepatic Uptake Mechanisms for Pravastatin and Temocaprilat / Toshihiko IKEDA/p159~160
          • Pharmacokinetics Stereoselective Metabolism of New Oral Anti-diabetic Agent Troglitazone Stereoisomers in Liver / Kenji KAWAI ; Tomoyo ODAKA ; Fujiko TSURUTA ; Taro TOKUI ; Toshihiko IKEDA ; Kan-ichi NAKAMURA/p160~161
          • Pharmaceutics Stability of a Carbapenem Antibiotic, Panipenem, in Aqueous Solution / Nobuya ITO ; Masahiko SUZUKI ; Masaru IKEDA/p161~162
          • Pharmaceutics Inhibitory Effects of Water-soluble Polymers on Precipitation of RS-8359 / Fusao USUI ; Kazuko MAEDA ; Akira KUSAI ; Kenji NISHIMURA ; Keiji YAMAMOTO/p162~162
          • Pharmaceutics The Effects of Drug Physico-chemical Properties on Release from Copoly (Lactic/Glycolic Acid) Matrix / Makoto MIYAJIMA ; Akiko KOSHIKA ; Jun-ichi OKADA ; Akira KUSAI ; Masaru IKEDA/p162~163
          • Pharmaceutics Effect of Polymer Crystallinity on Papaverine Release from Poly(L-lactic acid) Matrix / Makoto MIYAJIMA ; Akiko KOSHIKA ; Jun-ichi OKADA ; Masaru IKEDA ; Kenji NISHIMURA/p163~164
          • Agrochemicals Rice Blast Control with a Throw-in Packed Formulation Containing Pyroquilon / Mikio TSUDA ; Hiroshi OHTA ; Yukiyoshi TAKAHI ; Kinji TANIZAWA ; Akihiko KUNITOMO ; Yasuhiro TUJINO ; Harukazu TANAKA ; Takako MIURA ; Shigehiro KATO/p164~165
          • Agrochemicals Plant Growth-regulating Activities of Aminooxyacetate Derivatives / Masami OGAWA ; Tadashi AMAGASA/p165~166
          • Veterinary Zucker Diabetic Fatty (ZDF) Rats / Toshihiko FUJIWARA ; Kazushi ARAKI ; Eiko YORIKANE ; Yuka HAGISAWA ; Junichiro FUKUSHIGE ; Hiroyoshi HORIKOSHI/p166~166
          • Abstracts of contributions published in monographs //p167~168
          • Review Article Drug Treatment-1. Recent Progress in Diabetic Animal Experiments / Hiroyoshi HORIKOSHI/p167~167
          • Microbiology & Fermentation Biochemical and Fermentation Technological Approaches to Production of Pravastatin, a HMG-CoA Reductase Inhibitor / Nobufusa SERIZAWA ; Masahiko HOSOBUCHI ; Hiroji YOSHIKAWA/p167~168
          • Oral Presentations //p169~188
          • Honorary Awards //p189~190
          • Author Index //p191~198
      • 1999 (1)
    • 2000~2009 (1)

三共研究所年報の書誌情報

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https://dl.ndl.go.jp/info:ndljp/pid/3411035/1

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